Function Oriented Molecular Design: Dendrimers as Novel Antimicrobials.

نویسندگان

  • Sandra García-Gallego
  • Gianluigi Franci
  • Annarita Falanga
  • Rafael Gómez
  • Veronica Folliero
  • Stefania Galdiero
  • Francisco Javier de la Mata
  • Massimiliano Galdiero
چکیده

In recent years innovative nanostructures are attracting increasing interest and, among them, dendrimers have shown several fields of application. Dendrimers can be designed and modified in plentiful ways giving rise to hundreds of different molecules with specific characteristics and functionalities. Biomedicine is probably the field where these molecules find extraordinary applicability, and this is probably due to their multi-valency and to the fact that several other chemicals can be coupled to them to obtain desired compounds. In this review we will describe the different production strategies and the tools and technologies for the study of their characteristics. Finally, we provide a panoramic overview of their applications to meet biomedical needs, especially their use as novel antimicrobials.

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عنوان ژورنال:
  • Molecules

دوره 22 10  شماره 

صفحات  -

تاریخ انتشار 2017